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Atenolol-Chlorthalidone 50-25 Mg Tabs 100 By Mylan Pharma.

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Atenolol-Chlorthalidone 50-25 Mg Tabs 100 By Mylan Pharma.

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Atenolol-Chlorthalidone 50-25 Mg Tabs 100 By Mylan Pharma. This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXD1267459/RXB10028530
Size : 100
Selling UoM : EA
NDC: 00378-2063-01
UPC Barcode : 303782063011
Supplier: 0050000337 MYLAN PHARM
Supplier Material : 206301
Generic Code : 000420 ATENOLOL/CHLORTHALIDONE ORAL TABLET 50 M
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
Product Type : GRX Generic RX

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Product Description.:

M 63
tablet , white , scored , round round
Biconvex

TENORETIC? (atenolol and chlorthalidone) is for the treatment of hypertension. It combines the antihypertensive activity of two agents: a beta1-selective (cardioselective) hydrophilic blocking agent (atenolol, TENORMIN?) and a monosulfonamyl diuretic (chlorthalidone).

Inactive ingredients: magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate.

INDICATIONS

TENORETIC is indicated in the treatment of hypertension. This fixed dose combination drug is not indicated for initial therapy of hypertension. If the fixed dose combination represents the dose appropriate to the individual patient'sneeds, it may be more convenient than the separatecomponents.
DOSAGE AND ADMINISTRATION

DOSAGE MUST BE INDIVIDUALIZED. (See INDICATIONS.)

Chlorthalidone is usually given at a dose of 25 mg daily the usual initial dose of atenolol is 50 mg daily. Therefore, the initial dose should be one TENORETIC 50 tablet given once a day. If an optimal response is not achieved, the dosage should be increased to one TENORETIC 100 tablet given once a day.

When necessary, another antihypertensive agent may be added gradually beginning with 50 percent of the usual recommended starting dose to avoid an excessive fall in blood pressure.

Since atenolol is excreted via the kidneys, dosage should be adjusted in cases of severe impairment of renal function. No significant accumulation of atenolol occurs until creatinine clearance falls below 35 mL/min/1.73m2 (normal range is 100-150 mL/min/1.73m2) therefore, the following maximum dosages are recommended for patients with renal impairment. Creatinine Clearance Atenolol Elimination (mL/min/1.73m2) Half-life (hrs) Maximum Dosage15-35 16-27 50 mg daily < 15 > 27 50 mg every other day
HOW SUPPLIED

TENORETIC 50 Tablets (atenolol 50 mg and chlorthalidone 25 mg), NDC 0310-0115, (white, round, biconvex, uncoated tablets with TENORETIC on one side and 115 on the other side, bisected) are supplied in bottles of 100 tablets.

TENORETIC 100 Tablets (atenolol 100 mg and chlorthalidone 25 mg), NDC 0310-0117, (white, round, biconvex, uncoated tablets with TENORETIC on one side and 117 on the other side) are supplied in bottles of 100 tablets.
Storage

Store at controlled room temperature, 20-25?C (68-77?F) [see USP]. Dispense in well-closed, light-resistant containers.

SIDE EFFECTS

TENORETIC is usually well tolerated in properly selected patients. Most adverse effects have been mild and transient.The adverse effects observed for TENORETIC are essentially the same as those seen with the individual components.