Valley Medical Pharmacy 
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Ssd 1% Jar Cream 50 Gm By Dr Reddys Labs

Image 0 of Ssd 1% Jar Cream 50 Gm By Dr Reddys Labs Image 1 of Ssd 1% Jar Cream 50 Gm By Dr Reddys Labs

Ssd 1% Jar Cream 50 Gm By Dr Reddys Labs

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Ssd 1% Jar Cream 50 Gm By Dr Reddys Labs This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXD4478020/RXB10097430
Size : 50 GM
Selling UoM : EA
NDC: 43598-0210-55
UPC Barcode : 343598210551
Supplier: 0050000709 DR. REDDYS LABORATORIES, INC.
Supplier Material : 021055
Generic Code : 007669 SILVER SULFADIAZINE TOPICAL CREAM (G) 1
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
Product Type : GRX Generic RX

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Product Description.:

Cream , white
White to off-white

Indications And Clinical Uses :

For the adjunctive treatment of burns, skin grafts, incisions, leg ulcers and other clean lesions, abrasions, minor cuts and wounds. It is especially indicated in the treatment and prophylaxis of infection in serious burn victims.

Contra-Indications:

In patients with a history of hypersensitivity to silver sulfadiazine.:

Since sulfonamide derivatives are known to increase the possibility of kernicterus, silver sulfadiazine cream should not be used in pregnant women approaching or at term, in premature infants, or in neonates less than 2 months of age.

Precautions:

Following administration of silver sulfadiazine cream, absorption of sulfadiazine has been reported. In addition, small amounts of silver are absorbed over the course of repeated application of silver sulfadiazine cream. In extensively burned patients, serum sulfa concentrations and renal functions should be closely monitored.:

Silver sulfadiazine cream should be used with caution in patients with significant hepatic or renal impairment.

Leukopenia has been reported following the use of silver sulfadiazine cream, especially in patients with large burn areas (see Adverse Effects).

Drug Interactions :

Enzymatic Debridement: Silver sulfadiazine cream may inactivate topical enzymatic preparations used for debridement. Therefore, the use of concomitant systemic or alternative topical antimicrobial therapy should be considered.

Oral Hypoglycemic Agents and Phenytoin: Sulfa drugs may compete for the same degradation pathways utilized by some oral hypoglycemic agents and phenytoin. There is a possibility of half-life prolongation and decreased plasma clearance of these drugs, which may potentiate their activity.

Cimetidine: An increased incidence of leukopenia has been observed in patients receiving concomitant treatment with silver sulfadiazine cream and cimetidine.

Pregnancy: The safe use of silver sulfadiazine cream has not been established in pregnancy. The cream should be administered to pregnant women only when the physician decides that the potentially life-saving benefits of silver sulfadiazine therapy in the larger burn (extent greater than 20% body surface area) outweigh possible hazard to the fetus (see Contraindications).

Adverse Reactions:

:Leukopenia: Several cases of transient leukopenia have been reported in patients receiving silver sulfadiazine therapy. Leukopenia associated with silver sulfadiazine administration is primarily characterized by a decreased neutrophil count. Maximal white blood cell depression occurs within 2 to 4 days of initiation of therapy. Rebound to normal leukocyte levels follow onset of leukopenia within 2 to 3 days. Recovery is not influenced by continuation of silver sulfadiazine therapy. The incidence of leukopenia in various reports averages about 20% although an incidence as high as 55% has been noted.

Sulfonamides: During the treatment of burns over large body surfaces (greater than 20% body surface area), significant amounts of silver sulfadiazine are systemically absorbed. Therefore, it is possible that any adverse reactions associated with sulfonamides may occur.

Miscellaneous: A low incidence of other adverse reactions has been reported. This includes local burning sensation, rashes and pruritus, and rarely, interstitial nephritis