Product Description.:
A skin disease also known as solar keratoses. These lesions are the result of years of unprotected exposure to the sun's ultraviolet (UV) rays. Although you may have been extra careful about sun protection in the recent past, if you spend time in the sun when you were younger, you have put yourself at risk for developing AKs. Many adults have AKs, so rest assured that you are not alone.
AKs actually represent the earliest stages of squamous cell carcinoma (SCC). Since the 1960s the incidence of the SCC has been increasing 4%-8% per year. SCC affects about 100,000 Americans each year and 2,000 to 2,500 Americans die each year due to SCC of the skin.2
AK and sBCC lesions multiply at a faster rate than normal cells. Fluorouracil, the active ingredient in EFUDEX?, is believed to interfere with a cell's ability to reproduce. As a result, the unhealthy cells absorb the fluorouracil in EFUDEX? faster than healthy, normal cells.
IMPORTANT SAFETY INFORMATION
EFUDEX? (fluorouracil) Topical Solutions and Cream is recommended for the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Safety and efficacy in other indications have not been established.
EFUDEX is contraindicated in women who are, or may become, pregnant during therapy because of potential hazards to the fetus. Cases of miscarriage and birth defects have been reported in women who are pregnant.
The most frequent adverse events occur locally and may include itching, burning, soreness, tenderness, scaling, and swelling. Application to mucous membranes should be avoided due to the possibility of local inflammation and ulceration.
