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Bisoprolol/Hctz 5-6.25 Mg Tabs 100 By Unichem Pharma.

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Bisoprolol/Hctz 5-6.25 Mg Tabs 100 By Unichem Pharma.

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Bisoprolol/Hctz 5-6.25 Mg Tabs 100 By Unichem Pharma. This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXD4492252/RXB10100833/RXa188011/RXA320107
Size : 100
Selling UoM : EA
NDC: 29300-0188-01
UPC Barcode : 329300188011
Supplier: 0050000323 UNICHEM PHARMA (PGN)
Supplier Material : 018801
Generic Code : 021140 BISOPROLOL FUMARATE/HCTZ ORAL TABLET 5-6
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
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Product Description.:

UL, II
tablet , film-coated , pink , round round
DebossedBiconvex

ZIAC (bisoprolol fumarate and hydrochlorothiazide) is indicated for the treatment of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1-selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide).

Inactive ingredients include Colloidal Silicon Dioxide, Corn Starch, Dibasic Calcium Phosphate, Hypromellose, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polysorbate 80, and Titanium Dioxide. The 5 mg/6.25 mg tablet also contains Red and Yellow Iron Oxide. The 2.5 mg/6.25 mg tablet also contains Crospovidone, Pregelatinized Starch, and Yellow Iron Oxide.

INDICATIONS

ZIAC (bisoprolol fumarate and hydrochlorothiazide) is indicated in the management of hypertension.
DOSAGE AND ADMINISTRATION

Bisoprolol is an effective treatment of hypertension in once-daily doses of 2.5 to 40 mg, while hydrochlorothiazide is effective in doses of 12.5 to 50 mg. In clinical trials of bisoprolol/hydrochlorothiazide combination therapy using bisoprolol doses of 2.5 to 20 mg and hydrochlorothiazide doses of 6.25 to 25 mg, the antihypertensive effects increased with increasing doses of either component.

SIDE EFFECTS

Bisoprolol fumarate/H6.25 mg is well tolerated in most patients. Most adverse effects (AEs) have been mild and transient. In more than 65,000 patients treated worldwide with bisoprolol fumarate, occurrences of bronchospasm have been rare. Discontinuation rates for AEs were similar for B/H6.25 mg and placebo-treated patients.