Product Description.:
AP, 112
tablet , blue , round round
Levsin? tablets (hyoscyamine sulfate tablets USP) contain 0.125 mg hyoscyamine sulfate formulated for oral administration.
Levsin? is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids. The empirical formula is (C17H23NO3)2?H2SO4?2H2O and the molecular weight is 712.85.
Each tablet also contains as inactive ingredients: FD&C blue #1, lactose monohydrate, magnesium stearate, mannitol, starch and stearic acid.
INDICATIONS
Levsin? is effective as adjunctive therapy in the treatment of peptic ulcer. It can also be used to control gastric secretion, visceral spasm and hypermotility in spastic colitis, spastic bladder, cystitis, pylorospasm, and associated abdominal cramps. May be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries, diverticulitis, and acute enterocolitis. For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and functional gastrointestinal disorders. Also used as adjunctive therapy in the treatment of neurogenic bladder and neurogenic bowel disturbances (including the splenic flexure syndrome and neurogenic colon). Also used in the treatment of infant colic (elixir and drops). Levsin? is indicated along with morphine or other narcotics in symptomatic relief of biliary and renal colic as a ?drying agent? in the relief of symptoms of acute rhinitis in the therapy of parkinsonism to reduce rigidity and tremors and to control associated sialorrhea and hyperhidrosis. May be used in the therapy of poisoning by anticholinesterase agents.
SIDE EFFECTS
All of the following adverse reactions have been reported with hyoscyamine sulfate. Adverse reactions may include dryness of the mouth urinary hesitancy and retention blurred vision tachycardia palpitations mydriasis increased ocular tension loss of taste headache nervousness drowsiness weakness fatigue dizziness insomnia nausea vomiting impotence constipation bloated feeling abdominal pain diarrhea allergic reactions or drug idiosyncrasies urticaria and other dermal manifestations ataxia speech disturbance some degree of mental confusion and/or excitement (especially in elderly persons) short-term memory loss hallucinations and decreased sweating.
DRUG INTERACTIONS
Additive adverse effects resulting from cholinergic blockade may occur when Levsin? is administered concomitantly with other antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants or some antihistamines.
Antacids may interfere with the absorption of Levsin?. Administer Levsin? before meals antacids after meals.
