Product Description.:
G, VOR200
tablet , film-coated , white , oblong oblong
Debossed
Voriconazole is used to treat fungal infections.
Take Voriconazole by mouth, usually twice daily, or take as directed by your doctor. The dose and duration of treatment depend on your condition and response to therapy. Take Voriconazole on an empty stomach, at least one hour before a meal or one hour after a meal. Continue to take Voriconazole until the full prescribed amount is finished. Stopping the medication too early may result in reinfection.
Precautions
Tell your doctor your medical history, especially of: liver disease, intolerance to galactose or lactose, heart problems (e.g., irregular heartbeats including QTc prolongation), mineral/electrolyte imbalance (e.g., low blood levels of potassium, magnesium, or calcium), any allergies (especially to azole antifungal drugs such as itraconazole, ketoconazole). Voriconazole, especially when taken for long periods of time, may affect your vision. Your vision should be monitored closely while taking Voriconazole. Report any loss of vision, problems recognizing colors correctly, or any other vision problems promptly to your doctor. Voriconazole may make you dizzy or cause vision changes use caution engaging in activities requiring alertness such as driving or using machinery. Since Voriconazole may cause vision changes, do not drive at night while taking Voriconazole. Limit alcoholic beverages. Voriconazole may make you more sensitive to the sun. Avoid prolonged sun exposure, use a sunscreen and wear protective clothing when outdoors. Voriconazole is not recommended for use during pregnancy as it may cause fetal harm. Women should use a reliable form of birth control while taking Voriconazole. Consult your doctor for more details. It is not known whether Voriconazole passes into breast milk. Breast-feeding is not recommended while using Voriconazole. Consult your doctor before breast-feeding.
Side Effects
Fever, chills, nausea, diarrhea, dizziness, flushing, abdominal pain and headache may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: vision changes (e.g., blurring, color vision changes), sensitivity of eyes to light (photophobia). Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, fast/irregular pulse, sun sensitivity. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: yellowing eyes or skin, dark urine, unusual fatigue, change in the amount of urine, easy bleeding or bruising, fainting. An allergic reaction to Voriconazole is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions
Voriconazole is not recommended for use with rifamycin antibiotics (e.g., rifabutin, rifampin), carbamazepine, barbiturates (e.g., phenobarbital, mephobarbital), sirolimus, and ergot alkaloids (e.g., ergotamine, dihydroergotamine). Ask your doctor or pharmacist for more details. Other drugs besides voriconazole which may affect the heart rhythm (QTc prolongation in the EKG) include terfenadine, astemizole, cisapride, dofetilide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Tell your doctor of all prescription and nonprescription medication you may use, especially: cyclosporine, tacrolimus, phenytoin, sildenafil, cilostazol, tolterodine, blood thinners (e.g., warfarin), cholesterol-lowering drugs ( statins such as atorvastatin, lovastatin, simvastatin), anti-anxiety drugs (benzodiazepines such as midazolam, triazolam), calcium channel blockers (e.g., verapamil, dihydropyridines such as isradipine, felodipine), oral diabetic drugs (sulfonylureas such as glipizide, glyburide, tolbutamide), anti-cancer drugs (e.g., vinblastine, vincristine), proton pump inhibitors (e.g., lansoprazole, omeprazole, pantoprazole), HIV protease inhibitor drugs (e.g., amprenavir, nelfinavir, ritonavir, saquinavir), HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs such as delavirdine, efavirenz, nevirapine). Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual
