USES: Lansoprazole works by blocking acid production in the stomach. This medication is known as a proton pump inhibitor (PPI). It is used to treat acid-related stomach and throat (esophagus) problems (e.g., acid reflux or GERD, ulcers, erosive esophagitis, Zollinger-Ellison syndrome). Lansoprazole may also be used to treat ulcers due to the long-term use of certain drugs (nonsteroidal anti-inflammatory drugs or NSAIDs) for pain or swelling. In addition, this medication may be used in combination with antibiotics to treat certain types of ulcers caused by bacterial infection.
HOW TO USE: Take this medication by mouth, usually once daily, before a meal or as directed by your doctor. Do not crush or chew the capsules. Swallow the medication whole. If you have difficulty swallowing this medication whole, the capsule may be opened and the contents sprinkled onto soft food (e.g., applesauce, cottage cheese, yogurt), or emptied into a small amount (2 oz or 60 ml) of juice and taken as directed. Rinse the container with an additional small amount of juice and drink the contents to make sure the entire dose is taken. Do not chew the food/medication mixture or prepare a supply in advance this may destroy the drug and/or increase side effects. Antacids may be taken along with this medication, if needed. The dosage and length of treatment is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better. Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: Constipation or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: signs of vitamin B-12 deficiency with long-term (over 3 years) treatment (e.g., unusual weakness, sore tongue, numbness or tingling of the hands/feet). A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking lansoprazole, tell your doctor or pharmacist if you are allergic to it or to similar drugs (e.g., omeprazole, pantoprazole) or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, other stomach problems (e.g., tumors). Some symptoms may actually be signs of a more serious condition. Tell your doctor immediately if you have: heartburn combined with lightheadedness/sweating/dizziness, chest pain or shoulder/jaw pain (especially with trouble breathing), pain spreading to arms/neck/shoulders, unexplained weight loss. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: This drug should not be used with the following medication because very serious interactions may occur: atazanavir. If you are currently using this medication, tell your doctor or pharmacist before starting lansoprazole. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: cilostazol, theophylline, voriconazole, warfarin. Lansoprazole can decrease the effectiveness of certain drugs which require stomach acid in order to be absorbed. Before using this medication, consult your doctor or pharmacist on how to manage such a potential interaction if you are taking the following drugs: ampicillin, azole antifungals (e.g., ketoconazole, itraconazole), iron supplements. Based on information for similar drugs, lansoprazole may increase the amount of digoxin that is absorbed into your blood. Consult your doctor or pharmacist for details if you also take digoxin. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222.
