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Isosorbide Dinitrate 10 Mg Tab 1000 By West Ward Pharma

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Isosorbide Dinitrate 10 Mg Tab 1000 By West Ward Pharma

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Isosorbide Dinitrate 10 Mg Tab 1000 By West Ward Pharma This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXD1757541/RXB10019118
Size : 1000
Selling UoM : EA
NDC: 00143-1771-10
UPC Barcode : 301431771102
Supplier: Supplier Material : 177110
Generic Code : 000507 ISOSORBIDE DINITRATE ORAL TABLET 10 MG
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
Product Type : GRX Generic RX

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Product Description.:

W W, 771
tablet , white , scored , round round

SES: Isosorbide relaxes blood vessels allowing more blood to flow through. This reduces the workload on the heart and improves blood flow to the heart. Sublingual isosorbide tablets act quickly to relieve or prevent chest pain (angina).

HOW TO USE: At the first sign of chest pain, sit down and place one tablet under the tongue or between your cheek and gum allowing it to dissolve. The drug is absorbed directly through the lining of the mouth. Do not chew or swallow the tablet. Do not eat, drink or smoke while the isosorbide is in your mouth. Effects should begin in 2 to 5 minutes. If after 5 minutes there is no relief of chest pain, take another tablet. If there is no relief after taking three tablets in a 15 minute period, call your doctor immediately or go to a hospital emergency room. If you use isosorbide sublingual tablets to prevent an expected angina attack, you may place the tablet under the tongue 5 to 10 minutes before the stress or physical exertion that brings on the attack. This effect may last up to 1 hour. If you have been taking this medicine regularly for several weeks, do not suddenly stop using it. Stopping suddenly may bring on angina.

SIDE EFFECTS: Headache, dizziness, flushing, rapid heartbeat, or restlessness may occur as your body adjusts to the medication. If they persist or become bothersome, inform your doctor. To prevent dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Notify your doctor if you experience: blurred vision, dry mouth, skin rash, nausea. Headache is often a sign the medication is working. Treat headaches with an aspirin or non-aspirin pain reliever as recommended by your doctor. If the headaches continue or become severe, notify your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.

DRUG CLASS AND MECHANISM: Isosorbide dinitrate is in the class of drugs called nitrates and it used for treating and preventing angina or heart pain. Other nitrates include nitroglycerin (Nitrostat, Nitroquick, Nitrolingual, Nitro-Dur and others) and isosorbide mononitrate (Imdur, Ismo, Monoket). Isosorbide dinitrate is converted in the body to isosorbide mononitrate which is the active chemical.

Nitrates are vasodilators (dilators of blood vessels). Blood returning from the body in the veins must be pumped by the heart through the lungs and into the body's arteries against the high pressure in the arteries. In order to accomplish this work, the heart's muscle must produce and use energy (fuel), and this requires oxygen. Angina pectoris (angina) or heart pain is due to an inadequate flow of blood (and oxygen) to the muscle of the heart. Nitrates, including isosorbide dinitrate, correct the imbalance between the flow of blood and oxygen to the heart and the work that the heart must do by dilating (expanding) the arteries and veins in the body. Dilation of the veins reduces the amount of blood that returns to the heart that must be pumped. Dilation of the arteries lowers the pressure in the arteries against which the heart must pump. As a consequence of both effects, the heart works less and requires less blood and oxygen.

PREPARATIONS: Tablets (sublingual): 2.5, 5, 10 mg. Tablets (immediate release): 5, 10, 20, 30, 40 mg. Tablets (extended release): 40 mg. Capsules (sustained release): 40 mg

STORAGE: Isosorbide dinitrate should be stored at room temperature, 15-30 C (59-86 F).

PRESCRIBED FOR: Isosorbide dinitrate is used for the treatment and prevention of angina caused by coronary artery disease. Only sublingual tablets are used for immediate treatment of angina because the onset of action of oral isosorbide dinitrate is not fast enough. Isosorbide dinitrate sometimes is used for treating congestive heart failure.

DOSING: Isosorbide dinitrate tablets can be taken with or without food. The sublingual tablets should be dissolved under the tongue and should not be crushed or chewed. Tolerance (reduced effect after several doses) may develop, so a drug free period of at least 14 hours is recommended. The recommended doses of isosorbide dinitrate are:

* Tablets: 5-40 mg 2 or 3 times daily
* Tablets: (sublingual): 2.5-10 mg
* Tablets: (extended-release) and capsules (sustained-release): 40-80 mg once or twice daily.

DRUG INTERACTIONS: Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) increase the blood pressure lowering effects of isosorbide dinitrate and may cause excessive blood pressure reduction. Patients taking isosorbide dinitrate should not receive sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra). Severe blood pressure reduction, especially when changing posture, may occur when isosorbide dinitrate is combined with calcium channel blockers, for example, diltiazem (Cardizem, Tiazac, etc.) and verapamil (Calan, Verelan, etc.) whi