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California Licensed Drugstore. Our pharmacy is in business for over 25 years. Our website services our clients for more than 18 years.


Accept Credit Cards Online Pharmacy Since 1996
Valley Medical Pharmacy
630 Main Street (Store:9am to 5.45pm)
Brawley, CA 92227 eRx ID#0585957

1 (800) 322-0808 FAX: (760) 344-6321 Toll Free Fax: 1 (855) 322-0808,

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Prescription Drugs-J > Janumet > Janumet XR 100-1000MG 90 Tabs By Merck & Co

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Janumet XR 100-1000MG 90 Tabs By Merck & Co

Janumet XR 100-1000MG 90 Tabs By Merck & Co This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXB10102719/RXD4564118
Size : 90 
Selling UoM : EA
NDC: 00006-0081-54
UPC Barcode : 300060081545
Supplier: 0050000571 MERCK & CO / USHH PDP
Supplier Material : 008154
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
Product Type : BRX Branded RX

    CALL TO ORDER: 1 (800) 322-0808     Back


Product Description.: 81 tablet , film-coated , blue , oval oblong BiconvexDebossed DRUG CLASS AND MECHANISM: Janumet is a combination of two drugs, metformin and sitagliptin, that are used for reducing blood glucose (sugar) levels in individuals with type 2 diabetes. The FDA approved Janumet in March 2007. Insulin is a hormone produced by the pancreas. It limits blood glucose levels by reducing the amount of glucose released by the liver into the blood and by increasing the removal of glucose from blood by muscle and fat tissues. Type 2 diabetes results when there is reduced sensitivity of muscle and fat to the effects of insulin. When the diabetes progresses, the pancreas produces less insulin. Both defects result in increased levels of glucose in the blood. Metformin is an oral medication that lowers blood glucose by increasing the sensitivity of liver, muscle, fat, and other tissues to the effects of insulin. Increasing the sensitivity of tissues to insulin causes more glucose to be removed from blood and thereby reduces the level of glucose in the blood. In scientific studies, metformin reduced the complications of diabetes such as heart disease, blindness and kidney disease. Sitagliptin is an oral drug that reduces blood glucose levels in patients with type 2 diabetes. Following a meal, incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are released from the intestine, and their levels increase in the blood. GLP-1 and GIP reduce blood glucose by increasing the production and release of insulin from the pancreas. GLP-1 also reduces blood glucose by reducing the secretion by the pancreas of glucagon, a hormone that increases the production of glucose by the liver and raises the level of glucose in the blood. The net effect of increased release of GLP-1 and GIP is to reduce blood glucose levels. In addition, sitagliptin inhibits the enzyme, dipeptidyl peptidase-4 (DPP-4) that destroys GLP-1 and GIP and thereby increases the levels and activity of both hormones and thereby the release of insulin. As a result, blood glucose levels fall. STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F) PRESCRIBED FOR: Janumet is combined with diet and exercise to improve blood glucose levels in patients with type 2 diabetes. It is not be used for treating type 1 diabetes. DOSING: Janumet is taken twice daily with meals, and the starting dose is based on the patient's current dose of sitagliptin and metformin. The maximum dose of Janumet is 100/2000 mg daily. DRUG INTERACTIONS: Cimetidine (Tagamet), by decreasing the elimination of metformin from the body, can increase the level of metformin in the blood by 40%. This may increase the frequency of side effects from metformin and Janumet. PREGNANCY: There are no adequate studies of Janumet or the individual components in pregnant women. Most experts agree that insulin is the appropriate treatment for diabetes during pregnancy. NURSING MOTHERS: It is unknown whether sitagliptin is secreted in human breast milk. However, metformin is excreted into breast milk and can therefore be transferred to the nursing infant. SIDE EFFECTS AND PRECAUTIONS: The most common side effects of Janumet are abdominal pain, nausea diarrhea, vomiting, and hypoglycemia. Lactic acidosis is a serious side effect of metformin that occurs in one out of every 30,000 patients and is fatal in 50% of cases. The symptoms of lactic acidosis are weakness, trouble breathing, abnormal heartbeats, unusual muscle pain, stomach discomfort, light-headedness and feeling cold. Patients at risk for lactic acidosis include those with reduced function of the kidneys or liver, congestive heart failure, severe acute illnesses, and dehydration. Janumet should be discontinued immediately if lactic acidosis is suspected

Janumet XR 100 1000MG 90 Tabs By Merck & Co

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