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Cytomel 50 Mcg Tabs 100 By Pfizer Pharma.

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Cytomel 50 Mcg Tabs 100 By Pfizer Pharma.

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Cytomel 50 Mcg Tabs 100 By Pfizer Pharma. This Item Requires A Valid Order From A Physician Licensed in USA. Item Number.:RXD3713062/RXB10004591
Size : 100
Selling UoM : EA
NDC: 60793-0117-01
UPC Barcode : 360793117010
Supplier: 0050000308 PFIZER PHARM
Supplier Material : 011701
Generic Code : 006660 LIOTHYRONINE SODIUM ORAL TABLET 50 MCG
Fine Line Class : 850085008510 All Rx Products
Product Category : RX Pharmaceuticals
Product Type : BRX Branded RX

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Product Description.:

KPI, 117
tablet , white , round round
White to off-white

WARNING
Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even lifethreatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
DRUG DESCRIPTION

Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) sodium or triiodothyronine (T3, liothyronine) sodium or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine T4 contains four iodine atoms and is formed by the coupling of two molecules of diiodotyrosine (DIT). T3 contains three atoms of iodine and is formed by the coupling of one molecule of DIT with one molecule of monoiodotyrosine (MIT). Both hormones are stored in the thyroid colloid as thyroglobulin.

Thyroid hormone preparations belong to two categories (1) natural hormonal preparations derived from animal thyroid, and (2) synthetic preparations. Natural preparations include desiccated thyroid and thyroglobulin. Desiccated thyroid is derived from domesticated animals that are used for food by man (either beef or hog thyroid) and thyroglobulin is derived from thyroid glands of the hog. The United States Pharmacopeia (USP) has standardized the total iodine content of natural preparations. Thyroid USP contains not less than (NLT) 0.17 percent and not more than (NMT) 0.23 percent iodine, and thyroglobulin contains not less than (NLT) 0.7 percent of organically bound iodine. Iodine content is only an indirect indicator of true hormonal biologic activity.

Cytomel (liothyronine sodium) Tablets contain liothyronine (L-triiodothryonine or LT3), a synthetic form of a natural thyroid hormone, and is available as the sodium salt.

Twenty-five mcg of liothyronine is equivalent to approximately 1 gram of desiccated thyroid or thyroglobulin and 0.1 mg of L-thyroxine.

Each round, white to off-white Cytomel (liothyronine sodium) tablet contains liothyronine sodium equivalent to liothyronine as follows:

5 mcg debossed SKF and D14 25 mcg scored and debossed SKF and D16 50 mcg scored and debossed SKF and D17. Inactive ingredients consist of calcium sulfate, gelatin, starch, stearic acid, sucrose and talc.

INDICATIONS

Thyroid hormone drugs are indicated:

1. As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema and ordinary hypothyroidism in patients of any age (pediatric patients, adults, the elderly) or state (including pregnancy) primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter and secondary (pituitary) or tertiary (hypothalamic) hypothyroidism (see WARNINGS).

2. As pituitary thyroid-stimulating hormone (TSH) suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules subacute or chronic lymphocytic thyroiditis (Hashimoto's) and multinodular goiter.

3. As diagnostic agents in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy.

Cytomel (liothyronine sodium) Tablets can be used in patients allergic to desiccated thyroid or thyroid extract derived from pork or beef.

SIDE EFFECTS

Adverse reactions, other than those indicative of hyperthyroidism because of therapeutic ovserdosage, either initially or during the maintenance period are rare (see OVERDOSAGE).

In rare instances, allergic skin reactions have been reported with Cytomel (liothyronine sodium) Tablets.