24-Hour Heartburn Relief with One Pill a Day — Use as directed for 14 days.

Prilosec OTC is different from many over-the-counter heartburn treatments. It targets acid production by directly shutting down many active acid pumps, and it works for 24 hours with one pill a day. This means you can get heartburn relief around the clock with one pill a day.*

Facts about Prilosec OTC:

• It’s the first proton pump inhibitor (PPI) to be available over the counter for the treatment of frequent heartburn.
• It’s for people with frequent heartburn (two or more days per week).
• One pill a day works to relieve heartburn for up to 24 hours as part of a 14-day course of therapy.*
• Prilosec OTC is to be used once a day for 14 days, or as directed by your doctor.
• Prilosec OTC is available over the counter for frequent heartburn.

Proton Pump Inhibitors: How Prilosec OTC® Works

As the first over-the-counter proton pump inhibitor, Prilosec OTC is different from many other OTC heartburn treatments.

Prilosec OTC acts as proton pump inhibitors and is different from other over-the-counter heartburn medication.

The lining of your stomach produces acid through millions of tiny acid pumps. When you eat, these pumps switch on to produce the acid that breaks down food.

Prilosec OTC works by directly blocking many active pumps. Your stomach still produces enough acid to digest the food you eat. But by reducing the acid, Prilosec OTC lessens the chance that you will suffer from frequent heartburn. Prilosec OTC directly shuts down many active pumps and each daily dose works up to 24 hours. Use as directed as part of a 14-day course of therapy.

*It's possible with Prilosec OTC. Use as directed for 14 days for treating frequent heartburn. Not for immediate relief.